The content displayed is not going to change much but the connections between slides or scenes is completely different. There is a fluid link between different visual elements which is entertaining now, but I think there will be some clever adaptations where the connections actually convey much more meaning and information.
Slide based presentations are like wearing horse blinders so that your line of sight is very limited. Prezi opens up a whole world of possibility. This is a very cool tool. I can’t wait to see some of the more creative presentations done with it.